منابع مشابه
Barbara McClintock on Defining the Unstable Genome.
It is with this prescient statement that Barbara McClintock began the discussion of her classic 1953 GENETICS article describing how so-called “extragenic” components, now known as transposons, could alter the function of nearby genes. Precisely 30 years later she would be the sole winner of the Nobel Prize in Physiology or Medicine for her scrupulous studies of unexpected phenotypic changes sh...
متن کاملBarbara McClintock and the discovery of jumping genes.
The history of modern genetics begins with the experiments of Gregor Mendel (1822-1884). Mendel found that when hereditary traits were followed through successive generations of hybridisation, the numbers of offspring that resembled parental types were in simple numerical ratios relative to one another – 1:1, or 3:1, or 9:3:3:1, and so on. The most straightforward explanation of these numbers w...
متن کامل"The Origin and Behavior of Mutable Loci in Maize" (1950), by Barbara McClintock
"The Origin and Behavior of Mutable Loci in Maize," by Barbara McClintock, was published in 1950 in the Proceedings of the National Academy of Sciences [2] of the United States of America. McClintock worked at the Cold Spring Harbor Laboratory [3] in Laurel Hollow, New York, at the time of the publication, and in the article she describes her discovery of transposable elements in the genome [4]...
متن کاملMaize Genetics Barbara Mcclintock Completion of the Studs of the Allele Relations of Deficiency Mutants
During this year studies were completed of 13 mendelizing recessive mutants associated with homozygous small terminal deficiencies of the short arm of chromosome 9. All 13 mutants arose independently following breakage of the short arm of a chromosome 9 which resulted, in each case, in deletion of a small terminal segment. Seven of these mutants gave a paleyellow seedling phenotype (designated ...
متن کاملGENETICS: B. McCLINTOCK
7 Istrati, Gh., Compt. Rend. Soc. Biol., 129, 1010-1013 (1938). 8 Wagner-Jauregg, Th., Centralbl. f. Bakt., 144, I. Orig., 31-32 (1939). 9 Okell, C. C., and Blake, A. V., Jour. Path. & Bact., 33, 57-63 (1930). 10 Shwartzman, G., "Phenomenon of Local Tissue Reactivity," N. Y., 461 pp. (1937). 11 Ajo, C., Proc. Soc. Exper. Biol. & Med., 47, 500-501 (1941). 12 Sterges, A. J., Jour. Bact., 43, 317-...
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ژورنال
عنوان ژورنال: Annual Review of Genetics
سال: 1993
ISSN: 0066-4197
DOI: 10.1146/annurev.genet.27.1.1